Searchable abstracts of presentations at key conferences in endocrinology

ea0032p1040 | Thyroid (non-cancer) | ECE2013

Thyroid hormone elevates IL6 tissues content and causes hypoleptinemia

Biz Carolina , Oyama Lila Missae , Telles Monica Marques , do Nascimento Claudia Oller

Oxidative stress is regarded as a pathogenic factor in hyperthyroidism. IL6 has been described as acting as a protective intrahepatocellular against oxidative stress and mitochondrial dysfunction. On the opposite way leptin has been shown to increase oxidative stress. The impact of thyroid hormones on circulating cytokines levels has been demonstrated with conflicting results both in human and rats. Most of the studies concerned hyperthyroidism showed increased levels of IL6 c...